About angina

Too little oxygen reaching your heart muscle may lead to angina

Angina means your heart needs more oxygen

Your heart is a muscle. It needs oxygen to work. The arteries of your heart, also known as coronary arteries, provide oxygen-rich blood to your heart muscle so it can pump blood out to the rest of your body.

Angina may be a symptom of a heart problem called coronary heart disease (CHD), also known as coronary artery disease (CAD).

In CHD, the blood vessels in your heart become stiff and narrow. Angina usually comes on when too little oxygen reaches your heart muscle.

Symptoms of angina

Chronic angina is chest pain, discomfort, or pressure that may happen because of1,2:

These are not all of the possible causes of angina. Talk to your cardiologist about which activities are sources of angina for you.

What does angina feel like?

People experience angina in different ways1-3:

In women, angina can be different4:

Make a list of the symptoms you experience with angina and discuss them with your doctor. As an addition to your treatment, your cardiologist may be able to provide tips on how to prevent angina from occurring.

What is Ranexa?

Ranexa is a prescription medicine used to treat adults with angina that keeps coming back (chronic angina). Ranexa may be used with other medicines that are used for heart problems and blood pressure control.


Who should not take Ranexa?

Do not take Ranexa if:

What are the possible side effects of Ranexa?

What else do I need to know about taking Ranexa?

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch, or call 1‐800‐FDA‐1088.

Please see full Prescribing Information including Patient Information for Ranexa (ranolazine).


  1. Angina pectoris. American Heart Association website. www.heart.org/HEARTORG/Conditions/HeartAttack/SymptomsDiagnosisofHeartAttack/Angina-Pectoris-Chest-Pain_UCM_437515_Article.jsp. Accessed May 14, 2013.
  2. Morrow DA, Boden WE. Stable ischemic heart disease. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, PA: Saunders Elsevier; 2012:1210-1254.
  3. Angina. National Heart Lung and Blood Institute website. www.nhlbi.nih.gov/health/dci/Diseases/Angina/Angina_WhatIs.html. Accessed May 14, 2013.
  4. D’Antono B, Dupuis G, Fortin C, et al. Angina symptoms in men and women with stable coronary artery disease and evidence of exercise-induced myocardial perfusion defects. Am Heart J. 2006;151:813-819.